| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 |
| filingDate |
1979-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1981-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a6a387090e0080d703e961801ea686d |
| publicationDate |
1981-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4251541-A |
| titleOfInvention |
1-Substituted-3-arylthio-4-hydroxypyrrolidines |
| abstract |
Trans isomers of 1-substituted-3-arylthio-4-hydroxypyrrolidines and derivatives thereof having the formula: <IMAGE> are disclosed wherein R1 is hydrogen, lower-alkyl, -C(O)NH-lower-alkyl and -C(O)-NH-phenyl; R2 is lower-alkyl, cycloalkyl and phenylalkyl; Ar is phenyl and substituted phenyl and the pharmaceutically acceptable addition salts thereof. The compounds have antidepressant activity in animals. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4320137-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101182304-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5523415-A |
| priorityDate |
1979-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |