http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4242509-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-57 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 |
filingDate | 1979-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1980-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bbb9deef4e30c1ad9f3e515aea7647d |
publicationDate | 1980-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4242509-A |
titleOfInvention | Process for producing 7-amino-7-alkoxycephalosporins |
abstract | A 7-(5-amino-5-carboxyvaleramido)-7-methoxycephalosporin with amino and acid groups protected is reacted with PCl 5 or other agent capable of forming an imino halide; the resulting imino halide is thereafter reacted under essentially non-aqueous conditions with a primary loweralkanol of C 1 -C 4 or with methan-d 3 -ol, yielding nucleus bearing a 7-alkoxy group derived from the primary loweralkanol or methan-d 3 -ol. In situ acylation of the nucleus affords 7-acylamido-7-alkoxycephalosporins in good yield; these products can be deesterified to yield the corresponding acids, which exhibit antibacterial activity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4313945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4374134-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4656262-A |
priorityDate | 1979-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.