http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4233456-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ead2302413f783f81d0928441941552 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 1978-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59c0a3793976ffaf2676873afd5ac87e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2e2c3d808e5442b98a6ade8e4a8799b |
| publicationDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4233456-A |
| titleOfInvention | Process for the manufacture of optically active, optionally substituted 2-amino-2-phenylacetic acid |
| abstract | Optically active 2-amino-2-phenylacetic acid of the formula ##STR1## in which R 1 , R 2 and R 3 , which are identical or different, denote hydrogen, halogen, hydroxy, alkyl, acyl, or alkoxy, is prepared by asymmetrical transformation of a corresponding DL-aminophenylacetonitrile with L(+)-tartaric acid. To this end the corresponding DL-2-amino-2-phenyl-acetonitrile is reacted with approximately equimolar amounts of L(+)-tartaric acid in the presence of at least one alkanol having from 1 to 5 carbon atoms and/or at least one carbonyl compound at a temperature of from 0° to 50° C. and the mixture is stirred for 2 to 120 hours at the indicated temperature. The crystallized transformation product is separated, hydrolyzed by treatment with an acid and the desired product is isolated. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4350641-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4519955-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4415504-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5336805-A |
| priorityDate | 1977-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.