http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4233449-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 |
filingDate | 1979-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c4bb77762186382ad40e940233e63ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e349e0248a7265d5320f130620e1a3d8 |
publicationDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4233449-A |
titleOfInvention | 1-(8-Methyl-2-phenyl(or thienyl)-8-azabicyclo[3.2.1]octan-3-yl) ethanone |
abstract | Compounds of the tropane (8-azabicyclo[3.2.1]octane) series having an aromatic substitutent in the 2-position and a carboalkoxy group in the 3-position are prepared by reacting a tropane-3-carboxylate having a double bond in the 2,3-position with an aryl Grignard reagent. Transformations of the substituent on nitrogen are subsequently effected. Compounds where the 3-carboalkoxy group is in the exo configuration possess hypoglycemic activity, and those where the 3-carboalkoxy group is in the endo configuration possess narcotic antagonist activity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9318033-A1 |
priorityDate | 1979-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.