| abstract |
A method for treating or preventing metabolic bone disease characterized by loss of bone mass and of improving the calcium balance and calcium absorption of mammals, particularly of women in the post menopausal state, by administering at least one compound having the formulae <IMAGE> +TR <IMAGE> where R1, R2 and R4 are each selected from the group consisting of hydrogen, hydroxyl, lower alkyl, acyl and O-alkyl and R3 is selected from the group consisting of hydrogen, hydroxyl, keto, lower alkyl, acyl and O-alkyl. |