| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9dac02fc1594a58bccd5abb8e979b84 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
| filingDate |
1977-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1980-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cecbe0a4e0e82c2f026d91bb4dc4798c |
| publicationDate |
1980-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4217445-A |
| titleOfInvention |
5-Oxy-substituted derivatives of Psoralene useful in dermatology |
| abstract |
An improved process for obtaining 5-methoxy-psoralene from bergamot oil, a method for preparing the compound 5-hydroxy-psoralene from 5-methoxy-psoralene and a method of making novel psoralene derivatives by replacing the hydrogen atom of the 5-hydroxy group with an R group are disclosed. These compounds are prepared by reacting the 5-hydroxy-psoralene with a halide RX in the presence of sodium hydride. Compounds of particular interest are those of which the radical R is: alkanoyl of not more than 10 carbon atoms; orthoacetoxy-benzoyl; alpha thenoyl; O,O diethyl-phosphono; diethylaminoethyl, and 2'3'4'6' tetra alpha acetyl D-gluco pyranosyl. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100488493-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6734313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5360816-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5200425-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5962512-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4269851-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5405868-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4264478-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6613918-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011166217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4324703-A |
| priorityDate |
1976-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |