abstract |
A process is disclosed for preparing arylpropionic acids of formula Ar--CH(CH 3 )--COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar--C(OH)(CH 3 )--COOH or its amide, and converting the acid or amide to the product. |