| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95839c05a2da75a6ca35883c09571ff2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate |
1977-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1980-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd04117012a28d8bd7c091ae98eda2e8 |
| publicationDate |
1980-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4183852-A |
| titleOfInvention |
Process for preparing 25-hydroxycholesterol |
| abstract |
The synthesis of 25-hydroxycholesterol and 25-hydroxycholecalciferol from animal bile starting materials in which hyodeoxycholic acid or an ester thereof is converted to the 3β-hydroxy-5-cholenic acid alkyl ester, and this is converted to 3β-hydroxy-25-cyano-5-cholene by a series of steps by which the sterol nucleus is stabilized by placing a protecting group at the 3 position and then extending the chain from the carbon at the 24 position to a cyanide group at the 25 position. The compound so formed is subjected to a series of reactions by which it is transformed into 25-hydroxy-7-dehydrocholesterol which may then be irradiated with ultraviolet light to 25-hydroxycholecalciferol. The invention discloses new and improved processes for preparing these end products and also new compounds formed as intermediates and processes for preparing these intermediates. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010034781-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11407782-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006270645-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5468511-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010112030-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7897588-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011008297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11104701-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9670244-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2003268260-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9742215-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9717742-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149056-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010048944-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004019884-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004019884-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4336193-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9532994-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9683009-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006251735-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009035155-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279730-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4351767-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526737-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11117924-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8022052-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009220562-A1 |
| priorityDate |
1977-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |