| abstract |
2-Amino-cyclopent-1-ene-1-dithiocarboxylic acid derivatives of the formula, <IMAGE> (I) wherein R is C2-4 alkenyl, or C1-6 alkyl group having optionally a C1-4 alkoxy, hydroxy, carboxy and/or amino substituent, with the proviso that if R is an unsubstituted alkyl group, this group contains at least 5 carbon atoms, are prepared by reacting 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid or a salt thereof with an amine of the formula, R-NH2 (II) wherein R is as defined above. The new compounds of the invention exert dopamine- beta -hydroxylase inhibiting effects. |