| abstract |
There is presented peptide derivatives comprising polypeptides to which are bound via its functional side-chains penicilloyl residues of the formula <IMAGE> (I) wherein R signifies 2-pentenyl, n-pentyl, n-heptyl, allylthiomethyl, 5-amino-5-carboxypentyl, benzyl, alpha -carboxy benzyl, alpha -aminobenzyl, phenoxy benzyl, phenoxymethyl, alpha -phenoxy ethyl, alpha -phenoxypropyl, 2,6-dimethoxyphenyl, 2-ethoxy-1-naphthyl, 3-carboxy-2-quinoxazinyl, 5-methyl-3-phenyl-4-isoxazolyl, alpha -amino-p-hydroxy benzyl, 3-(2-chlorophenyl)-5-methyl-4-isoxazolyl, 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl, 3-(2-chloro-6-fluoro-phenyl)-5-methyl-4-isoxazolyl, alpha -carboxy-3-thienylmethyl or alpha -sulphonylbenzyl. |