Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-085 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-28 |
filingDate |
1978-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1979-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d07b877519938ca1c117e69b923652b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1efe6d58c2ccf5193283991bab925830 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5541e3f3cd4951d572cb120d47768152 |
publicationDate |
1979-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4166905-A |
titleOfInvention |
O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents |
abstract |
There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula <IMAGE> I wherein Z is etherified hydroxyl and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114773309-A |
priorityDate |
1975-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |