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filingDate 1976-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1979-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1979-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4158049-A
titleOfInvention Antigen fraction of Schistosoma mansoni eggs suitable for testing for schistosomiasis
abstract Schistosoma mansoni eggs are ground to liberate soluble egg antigens which are fractionated and purified by absorption, gel filtration and/or ion exchange chromatography, and then radioactively labelled with 125I. A fraction, identified as MSA1, is specific to the mature egg stage of Schistosoma mansoni and thus can be used to detect the presence of antibody to mature Schistosoma mansoni eggs in a patient's serum even as compared with mature eggs of different Schistosoma (species specific) or of Schistosoma mansoni worms but not mature eggs (stage specific).
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