| abstract |
{PG,1 The tricyclic intermediate {r1 {tc,1 {tr,29 {rb {rd,dd00335588 {db,b {sd,11 {sb,15 O{A,5 {M,1 {A,2 {LS,8 {SD,26 {SB,4 O{A,1 {BN,D {SD,5 {SB,15 O{A,2 {BL,8 {BL,B {RD,BFF1 {MR,1 {RD,335588BBDD/1 {A,2 {RD,00335588BB {A,4 {BN,0 {A,4 {RD,335588CCCC {A,2 {DB,0 {US,5 {SB,4 O{RE (I) {PS {PS is prepared in a three step sequence from the bicyclic intermediate {r1 {tc,1 {tr,28 {rb {rd,033 {a,1 {sd,15 {sb,4 CO{HD 2{L H{A,3 {BU,00 {RD,DD00335588BB {A,2 {DB,B {SD,11 {SB,14 O{A,5 {BN,0 {A,5 {RD,335588CCCC {A,2 {DB,0 {US,5 {SB,4 O{A,5 {BU,88 {SD,15 {SB,4 H{RE (II) {PS {PS The key step of this process involves the addition of a Grignard reagent to a mixed anhydride. Tricyclic compound of formula (I) may be readily converted by known methods to valuable steroids. |