| abstract |
The disclosure includes novel compounds which differ from the known prostaglandins PGF 2 α, PGF 2 β, PGE 2 , PGA 2 , and PGB 2 in that the carbon-carbon double bond in the carboxyl-terminated chain of the novel compounds is in the 4,5-position rather than in the 5,6-position, and in that there is a phenoxy or substituted phenoxy group in the other chain of the novel compounds. These novel compounds are useful for a variety of pharmacological purposes, including abortion, labor induction, and reduction of gastric secretion. |