abstract |
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: <IMAGE> WHEREIN R1 is a multivalent hydrocarbon radical, R2 and R3 are hydrocarbon radicals with at least one of R2 or R3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents. |