| abstract |
Esters of 2-substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes represented by the following formula: ##STR1## where R' is --CH 2 --CH═CH 2 , --CH 2 --CH(OH)--CH 2 OH, ##STR2## where Y is either O or S, or ##STR3## where R 4 and R 5 are independently hydrogen, alkyl having 1 to 6 carbon atoms, phenyl, or benzyl, or together R 4 and R 5 form an alkylene bridge having 4, 5 or 6 carbon atoms; one of R 2 and R 3 is hydrogen and the other is hydrogen, methyl, or ethyl, or together R 2 and R 3 are methylene. The compounds have anti-inflammatory, analgesic, and antipyretic activities and, accordingly, are useful in the treatment of inflammation, pain and/or pyrexia. |