| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ce7118d38871ab44cb2e76537e4ed1f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-15 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-157 |
| filingDate |
1976-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1978-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b72446eafd332d1df45227957e459040
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5824866a04b3738744c4b1263b949826 |
| publicationDate |
1978-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4110442-A |
| titleOfInvention |
2-phosphonoxy-4-trifluoromethylbenzoic acid derivatives and pharmaceutical compositions containing same |
| abstract |
2-OR-4-trifluoromethylbenzoic acid wherein R is phosphonoxy. n The compounds are useful in the treatment of pathological cardiovascular conditions, particularly in the prophylaxis of the thromboembolic diseases. n The compounds are made by reacting m-trifluoromethyl phenol with potassium carbonate and carbon dioxide at an elevated temperature and pressure and, reacting the 2-OH compound with a phosphonating agent. n The invention also embraces pharmaceutical compositions in which the compounds constitute the effective agent and a method of treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100503267-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9108490-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4397790-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4542011-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5262299-A |
| priorityDate |
1976-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |