http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4101675-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f2ed19fccd5a1a9ea5e6d7846459e43 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C281-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C281-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 |
| filingDate | 1976-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1978-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4b2bb561a73c6fd4811648a699a974 |
| publicationDate | 1978-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4101675-A |
| titleOfInvention | Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method |
| abstract | The invention relates to compounds of the general formula: <IMAGE> I in which one double bond is present between the carbon atom of the quanidine moiety and one of the adjacent nitrogen atoms and R0 stands for hydrogen, halogen, hydroxy, alkoxy or alkyl (1 to 6 C), R1, R2 for halogen, hydroxy, alkyl (1 to 4 C) or alkoxy (1 to 4 C), R3, R3', R3'' for hydrogen or alkyl (1 to 4 C), on the understanding that one of the substituents R3, R3' or R3'' is absent because of the presence of the double bond, R4 for hydrogen, alkyl (1-4 C), hydroxy, alkoxy (1-4 C) or amino optionally substituted with one or two alkyl (1 to 4 C) groups, R5, R6 for hydrogen, alkyl (1-6 C), acyl or R5 + R6 together represent an alkylidene, cyclic alkylidene or aralkylidene group, as well as the acid addition salts thereof, PROVIDED THAT, IF R4 stands for methyl and R0, R3, R3'', R5 and R6 for hydrogen, R1 and R2 may not represent methyl simultaneously, having a strong and long-acting anti-hypertensive activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6025349-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5001157-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4812466-A |
| priorityDate | 1973-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 361.