http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4099002-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 |
| filingDate | 1974-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1978-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b7ede875dab8acb975e7bc28ac5361 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33e1060fde55e704cdefb2ee5c487034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d1eeba5f1525ca3c95b083b831ba770 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b0d175ea1245e597ca3daa58a892de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7092184ee3f9ba85a5518635be287551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1210b75bf397f4d75511616c7c876e1a |
| publicationDate | 1978-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4099002-A |
| titleOfInvention | Quinazolinone derivatives and a process for production thereof |
| abstract | 3,4-Dihydro-2(1H)-quinazolinone derivatives of the formula, ##STR1## wherein R 1 and R 2 signify individually a hydrogen atom, a lower alkyl group, a lower alkoxy group, a nitro group, a trifluoromethyl group, a lower alkylthio group, a lower alkylsulfonyl group or a halogen atom; R 3 signifies a phenyl group, a halophenyl group, a lower alkylphenyl group, a lower alkoxyphenyl group, a trifluoromethylphenyl group, a lower cycloalkyl group, a lower cycloalkenyl group, a pyridyl group, a pyrrolyl group, a furyl group, a thienyl group or a naphthyl group; R 4 signifies a lower alkyl group, a lower alkenyl group, an aralkyl group, a lower cycloalkylalkyl group, a lower cycloalkyl group, a lower alkoxyalkyl group, a lower alkylthioalkyl group, a lower hydroxyalkyl group, a lower alkanoyloxyalkyl group, a phenyl group, a halophenyl group, a trifluoromethylphenyl group, a lower alkylphenyl group a lower alkoxyphenyl group, a pyridyl group or a group of the formula ##STR2## wherein n signifies an integer of 1 to 4; and R 5 and R 6 signify individually a lower alkyl group, provided that they may form together with the adjacent nitorgen atom an optionally substituted 5- or 6-membered heterocyclic ring, which may further contain a hetero atom); and R signifies a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkoxyalkyl group, a lower alkylthioalkyl group, an aralkyl group, a lower cycloalkylalkyl group, a lower trihalomethylalkyl group or a group of the formula ##STR3## (wherein n, R 5 and R 6 signify the same as defined above), which have excellent pharmacological properties such as central nervous system depressant, anti-inflammatory, analgestic and anti-microbial activities, can be produced by reducing a compound of the formula, ##STR4## wherein R, R 1 , R 2 , R 3 and R 4 have the same meanings as defined above; and X 1 , X 2 and X 3 signify individually a halogen atom, or by the substitution reaction of the ring nitrogen atom of a 1 or 3-unsubstituted 3,4-dihydro-2(1H)-quinazolinone derivative. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6124302-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890166-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9403827-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714249-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6645971-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8969351-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9624247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4159330-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6423718-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8440693-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9051279-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9550796-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9073898-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5556860-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9556180-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011230457-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4522945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9365576-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6184377-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4335127-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6429311-B2 |
| priorityDate | 1970-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 346.