http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4097678-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 |
filingDate | 1976-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1978-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796546ad9939b4c5657681acc0d5f3f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1729435486a850e42e7e15d01cae4f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_becd40a85bc8f9d67be7cf7d0969f7af |
publicationDate | 1978-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4097678-A |
titleOfInvention | Δ9 (11) -5α-D-homo-20-keto steroids |
abstract | 3α-Hydroxy and 3α-acyloxy- Δ 9 (11) -5α-D-homo-20-ketopregnenes of the formula ##STR1## wherein R is hydrogen or acyl, R 1 is hydrogen or methyl and R 2 is methyl or ethyl, are produced by esterifying a corresponding 3β-hydroxy-5α-20-keto pregnane of the formula ##STR2## wherein R 1 and R 2 have the values given above, with m-iodo-benzoic acid with inversion of the 3β-oxy group to a 3α-oxy group; chlorinating the thus-produced 3α-m-iodobenzoyl ester with dichloroiodobenzene under irradiation; and treating the reaction product with a dehydrohalogenating silver salt. Optionally thereafter, the 3α-iodobenzoyl group is split off in a conventional manner to produce the corresponding 3α-hydroxy steroid and optionally the thus-produced 3α-hydroxy steroid is esterified to produce a desired 3-ester thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6787659-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4260464-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7009063-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005004376-A1 |
priorityDate | 1975-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.