http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4088762-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_defc133ee3e61b82d9f0ab05d2d1135c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-90 |
| filingDate | 1976-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1978-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_335737783efa9787c8f4167fb9fedc94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c536cf88d6c18ac2470b804bf2fd04c |
| publicationDate | 1978-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4088762-A |
| titleOfInvention | 6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones |
| abstract | Compounds of the general formula: ##STR1## in which X represents A STRAIGHT OR BRANCHED CHAIN ALKYL OR ALKOXY GROUP, n A hydroxymethyl group, n A cycloalkoxy group, n A hydroxyl group, n A chlorine atom, n A piperidino group, n A pyrrolidino group n A cycloalkyl group, n An aryloxy group, n A fluorine atom, n An amino or substituted amino group, n A morpholino group, n A 1,2,3,6-tetrahydropyridino group, n A 4-[3-azabicyclo(3,2,2)-nonyl] group, or a 4-(piperazin-1-yl) or 4-(4-substituted-piperazin-1-yl) group of the formula ##STR2## in which R═H, lower alkyl of 1-5 carbon atoms, aryl, substituted aryl, aralkyl, cinnamyl, acyl, ethoxy-carbonyl, aroyl or substituted aroyl and n is an integer from 1 to 5 except that when n is 1 X is not an alkyl group of 1 to 3 carbon atoms or an alkoxy group of 1 or 2 carbon atoms or a chlorine atom in the 4'-position, or an amino or acylated amino group in positions 2', 3' or 4'; and when n= 2 the groups X cannot both be methyl or both be methoxy in the 2' and 5' positions, nor can X be a chlorine atom in both the 2' and 4' positions or the 3' and 4' positions, and when n= 3, X cannot all three be methoxy. These compounds have anti-hypertensive activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4353905-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4189578-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4624951-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5376656-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-609922-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4551455-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4289774-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4888169-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4246403-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4904664-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4954501-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4271163-A |
| priorityDate | 1971-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 369.