http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4086230-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-20 |
| filingDate | 1977-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1978-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79e0ff8506bb5ffb70f07e048b6e55c6 |
| publicationDate | 1978-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4086230-A |
| titleOfInvention | 1,5-Dihydro-7-aryl-as-triazine[4,3,-α][1,4]benzodiazepin-1-ols |
| abstract | Compounds of the formula: ##STR1## wherein R 1 is alkyl of 1 to 3 carbon atoms, inclusive; wherein R 2 is hydrogen, methyl or ethyl; wherein R 3 is hydrogen, fluoro, chloro, bromo, nitro and -CF 3 ; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, 2,6-difluorophenyl, and 2-pyridyl, are prepared by treating a hydrazino compound of the formula: ##STR2## with a carbonyl compound II: ##STR3## wherein R 1 is defined as above, and R', R" are alkyl of 1 to 3 carbon atoms, inclusive, or the group ##STR4## is a cyclic acetal, such as ##STR5## to give a compound of formula III: ##STR6## wherein R 1 , R 2 , R 3 , R', R" and Ar are defined as above, and cyclizing compound III to give the compound IV above. n Compounds III and IV, including the pharmacologically acceptable acid addition salt of these compounds, have sedative, anxiolytic and muscle-relaxing activity and can be used for the treatment of anxieties or muscle strains of mammals, including man. |
| priorityDate | 1977-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 278.