Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ede6dfd510f800f051b3578956a2999 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103 |
filingDate |
1976-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1978-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6261e74ccccc4e22ffbbd4a7992b6db3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac80edf3984ba14df457f4346983a020 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ce37dbd6f4ea42559e0e47cf7f6ebc7 |
publicationDate |
1978-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4083967-A |
titleOfInvention |
Nona- and decapeptides |
abstract |
Novel peptide compounds of the formula Glu-His-X3-X4-X5-X6-X7-X8-Pro-W are provided together with their acid addition salts and their complexes with pharmaceutically acceptable metals. The compounds are LH-RH analogues and together with their salts and complexes exhibit LH-RH agonist activity. In the formula X3 and X5 are the same or different and each is phenylalanyl optionally substituted in the benzene ring; X4 and X6 are the same or different and each is selected from glycyl, alanyl (D- or L-) and asparaginyl; X7 is a radical of a neutral hydrophobic non-sulphur containing non-heterocyclic amino acid; X8 is a radical of a basic amino acid or is glycyl or phenylalanyl optionally substituted in the benzene ring; and W is selected from glycine amide and a group -NR1R2. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4443368-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8401771-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2580174-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5238917-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5824646-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5840685-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4751215-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4275001-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-391811-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4762717-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4647552-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4647553-A |
priorityDate |
1973-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |