| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a333e6344b62fb21a7c1ee592b165fca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 |
| filingDate |
1975-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1978-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2246f4f453f318c9519236c1aae10156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8947f56cc42c9a0c181075f6ab12fd7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_579534dbd4d150a77c8701f529c77030 |
| publicationDate |
1978-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4075337-A |
| titleOfInvention |
Methods of combatting bacterial infections in warm-blooded animal with cephalsporin R-sulfoxide |
| abstract |
R-sulfoxides of the formulae <IMAGE> <IMAGE> +TR <IMAGE> wherein <IMAGE> represents an usual penicillin or cephalosporin amide group and X is selected from the group consisting of hydrogen, hydroxy, an alkanoyloxy and the residue of a nucleophilic agent and their salts and esters are prepared by oxidation of the corresponding penicillins and cephalosporins to convert the sulfur atom in the ring to a sulfoxide group and separating and isolating the penicillin- or cephalosporin R-sulfoxide so formed from the reaction mixture or by acylation of the free amino group of the intermediate 6-aminopenicillanic acid R-sulfoxide and 7-aminocephalosporanic acid R-sulfoxide and derivatives. A preferred straight oxidation method is the photosensitized oxygenation method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4558124-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4237128-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4275062-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4399131-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5869067-A |
| priorityDate |
1972-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |