| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 |
| filingDate |
1976-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1978-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9efd4daf6ce35f95a50121f17bb4a3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccbfff221e0c34f4597ba9ac8ef95c2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42dc5d3b4e1a7bfed1385fe248b463af |
| publicationDate |
1978-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4075214-A |
| titleOfInvention |
Preparation of leurosidine and novel leurosidine 4'-ethers and esters |
| abstract |
Vincaleukoblastine (VLB, vinblastine) is converted to leurosidine, its 4' epimer, by reaction with thionyl chloride to form a bis-sulfite ester followed by treatment of the bis-sulfite ester with silver perchlorate. The bis-sulfite ester is covertible to novel 4' ethers by treatment with a lower alkanol or 4' esters of leurosidine perchlorate with acetic anhydride. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4596676-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4322351-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4490378-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4410459-A |
| priorityDate |
1976-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |