| abstract |
The invention provides novel phenylacetic acid derivatives of the formula: <IMAGE> in which X and Y are the same or different and each represents halogen and R represents hydroxyl, alkoxy of 1 to 4 carbon atoms, a radical of formula R1-NH-CnH2n-O-, in which n is an integer from 1 to 4 and R1 is hydrogen or an alkanoyl radical R2CO-, in which R2 is alkyl of 1 to 4 carbon atoms, a radical of formula R4NH-, in which R4 is hydrogen or -CmH2mOH, where m is an integer from 1 to 3, or a radical of formula: <IMAGE> +TR <IMAGE> -OCmH2m-COOR2 or -O(CH2)p-Z radical, where n, m and R2 have the meanings given above, p is 0 or 1, and Z is a saturated or unsaturated ring with 6 ring atoms, one of which can be nitrogen, and which can carry from 1 to 3 methyl radicals, and the addition salts which such a derivative which contains a salifiable basic group forms with pharmaceutically acceptable acids and a process for their preparation. These compounds are useful as hypolipaemic and hypocholesterolaemic agents. |