http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4066758-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-19 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 |
| filingDate | 1976-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1978-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2364a879f29ed64a822540b8dbe13caa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3e5f902504bfc0046e40b4f62aa49f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffcd789ffe38d2bb5708ebdf56693b80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21921c6ab5336cf7926d3285d38b3671 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c2f1c2a1fbac9fb320144d736282fd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8cd8a30dc672facc5f47449f70c904f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4b5000c7a5daa7720d3eccf05a4d828 |
| publicationDate | 1978-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4066758-A |
| titleOfInvention | N2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof |
| abstract | N2-naphthalenesulfonyl-L-arginine esters and amides having the formula <IMAGE> 1 or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the class consisting of (1) alkoxy, alkenyloxy, cycloalkoxy and halogenated alkoxy, respectively containing not more than 10 carbon atoms, aralkyloxy of not more than 15 carbon atoms, and alkoxy of not more than 10 carbon atoms substitured with an alkoxy group of not more than 10 carbon atoms; <IMAGE> (2) wherein R1 and R2 are members selected from the class consisting of hydrogen, alkyl, aryl, alkenyl and cycloalkyl, respectively containing not more than 10 carbon atoms, and aralkyl and cycloalkylalkyl, respectively containing not more than 15 carbon atoms, and substituted alkyl containing not more than 20 carbon atoms, said substituent being selected from the class consisting of alkoxy, alkoxycarbonyl, acyl, acyloxy, arylcarbamoyl and N,N-polymethylenecarbamoyl, respectively containing not more than 10 carbon atoms, and carboxy; and <IMAGE> (3) wherein Z is a divalent group containing up to 10 carbons atoms, which consists of more than one group selected from the class consisting of methylene -CH2-, monosubstituted methylene <IMAGE> wherein R3 is selected from the class consisting of alkyl, acyl, alkoxy, and alkoxycarbonyl, respectively containing not more than 10 carbon atoms, and carbamoyl; and disubstituted methylene <IMAGE> wherein R4 and R5 are alkyl groups of not more than 10 carbon atoms, and which may further contain at least one member selected from the class consisting of oxy-O-, thio -S-, cycloalkylene of not more than 10 carbon atoms, imino <IMAGE> alkyl-substituted imino <IMAGE> wherein R6 is an alkyl group of not more than 10 carbon atoms, acyl-substituted imino <IMAGE> wherein R7 is an alkyl group of not more than 10 carbon atoms, and phenylene <IMAGE> which may be arranged in any order and complete the <IMAGE> ring together with the said methylene, monosubstituted methylene or disubstituted methylene; and R' is a member selected from the class consisting of 1-naphthyl substituted alkoxy or alkoxycarbonyloxy, respectively containing not more than 10 carbon atoms; and 2-naphthyl substituted with alkoxy or alkoxycarbonyloxy, respectively containing not more than 10 carbon atoms. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4173630-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6277863-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6087375-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5371091-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5332822-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5942620-A |
| priorityDate | 1974-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 497.