abstract |
2-(2-Hydroxyethyl)tetrahydro-1,4-oxazines and quaternary salts thereof having the formula: <IMAGE> WHEREIN Ar and Ar1 are the same or different and are unsubstituted and substituted aryl, said substituent being a halogen atom, R represents a lower alkyl group having from 1 to 4 carbon atoms, R1 is zero when X(-) is zero or is an alkyl group of from 1 to 4 carbon atoms which is the same or different from R, as defined above, and X(-) is zero when R1 is zero or is selected from the group consisting of Cl(-), Br(-), I(-) and CH3SO4(-) when R1 is lower alkyl, as defined above, is described. These compounds are useful for treating spasmodic syndromes. |