http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4061653-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-52 |
| filingDate | 1975-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1977-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c4f0134e1ef369b542c753ef73bbb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cfedeb78d4ff96319c6dba9b26319f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_713b00f0c2e4f1509843b846f90cd55a |
| publicationDate | 1977-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4061653-A |
| titleOfInvention | 1-Substituted-3-amino-pyrazol-5-ones |
| abstract | 1-Substituted-3-amino-pyrazol-5-ones of the formula <IMAGE> (I) or a pharmaceutically acceptable non-toxic salt thereof wherein R is A. PHENYL SUBSTITUTED BY ONE OR TWO IDENTICAL OR DIFFERENT SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, PHENYL, TRIFLUOROMETHYL, TRIFLUOROMETHOXY, NITRO, CYANO, FLUORO, BROMO, IODO, LOWER ALKYLAMINO, A CARBONAMIDO MOIETY OF THE FORMULA <IMAGE> and a sulphonamido moiety of the formula <IMAGE> wherein R1 and R2 are each hydrogen or straight or branched chain alkyl of 1 to 4 carbon atoms, or R1 and R2 together with the nitrogen atom to which they are attached may be linked together to form a 5-, 6- or 7-membered heterocyclic ring wherein the nitrogen atom is the only heteroatom or wherein oxygen is also present as a ring member; B. PHENYL HAVING AN ANNELLATED BRANCHED OR UN-BRANCHED, SATURATED OR UNSATURATED, 5-, 6- OR 7-MEMBERED ISOCYCLIC OR HETEROCYCLIC RING WHEREIN THE HETEROCYCLIC RING HAS ONE OR MORE OXYGEN HETEROATOMS AND/OR ONE OR MORE SULPHUR HETEROATOMS, SAID PHENYL RING BEING OTHERWISE UNSUBSTITUTED OR CHLOROSUBSTITUTED; C. PHENYL SUBSTITUTED BY SOn-alkyl wherein n is zero, 1 or 2, straight or branched chain alkoxy or - O -(CH2)n',-N(alkyl)2 wherein n' is 2 or 3; D. PHENYL SUBSTITUTED BY 2 IDENTICAL SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF ALKOXY OF 1 TO 4 CARBON ATOMS AND TRIFLUOROMETHYL; E. PHENYL HAVING 2 DIFFERENT SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, PHENYL, HALOGEN, ALKOXY, TRIFLUOROMETHYL, TRIFLUOROMETHOXY, LOWER ALKYLAMINO, NITRO, CYANO, -SOn-alkyl wherein n is zero, 1 or 2, a carbonamido moiety of the formula <IMAGE> and a sulphonamido of the formula <IMAGE> wherein R3 and R4 are each hydrogen or alkyl; F. TRICHLOROPHENYL; G. NAPHTHYL HAVING 1 OR 2 IDENTICAL OR DIFFERENT SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF HALOGEN AND ALKYL; OR H. UNSUBSTITUTED beta -NAPHTHYL, ANTHYRYL OR PHENANTHRYL, ARE PRODUCED BY REACTING A HYDRAZINE OF THE FORMULA R-CH2-NH-NH2 wherein R is as above defined with an acetic acid derivative of the formula <IMAGE> wherein X is hydroxy, alkoxy, aralkoxy, amino or alkylamino; and either a. Y' is hydrogen and Y'' is cyano; b. Y' and Y'' together form the moiety <IMAGE> wherein Y is alkoxy, aryloxy, aralkoxy, alkylmercapto, aralkylmercapto or amino. |
| priorityDate | 1972-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1008.