| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 |
| filingDate |
1975-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1977-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7557744dedad6b22e2e3795a56b1a3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71ff4701a49b2457b80629885a3138e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3f493406718635eaeb06aacf79e542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_941ce4acc9064540e32daec45aa95558 |
| publicationDate |
1977-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4061650-A |
| titleOfInvention |
5-Trihalogenomethyl-4,5-dihyro-oxazole-4-carboxylic acid esters |
| abstract |
Alkyl (or aralkyl) α-isocyanoacetate is condensed with a trihalogenoacetic aldehyde or its hydrate in the presence of an amine to give trans-4-alkoxycarbonyl(or aralkyloxycarbonyl)-5-trihalogenomethyl-2-oxazoline. The oxazoline compound is hydrolyzed under acidic conditions to give threo-γ,γ,γ-trihalogenothreonine, which is then subjected to catalytic or electrolytic reduction. The above-mentioned reactions can be carried out stereoselectively and threo-threonine is thereby obtained without by-products such as allo-threonine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034649-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017189586-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10550074-B2 |
| priorityDate |
1974-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |