http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4055593-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-935 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
| filingDate | 1975-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1977-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac69d5c2261e32568c442ea1d6a4260a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_754e61fb20b4e50c74fad7803fc2ede8 |
| publicationDate | 1977-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4055593-A |
| titleOfInvention | Alkyl diethers of prostaglandins |
| abstract | Novel alkyl diethers of prostaglandins of the formula; <IMAGE> wherein R1 is hydrogen or lower alkyl; R2 and R6 are hydrogen when Y is a single bond and R2 and R6 are absent when Y is a double bond; R3 is keto, <IMAGE> R4 is hydrogen or <IMAGE> <IMAGE> <IMAGE> R'9 is hydrogen or lower alkyl; R'10 is lower alkyl; R'11 is lower alkyl; Z1 is cis or trans -CH=CH- or -CH2CH2-; Z2 is trans -CH=CH- or -CH2CH2-; X is a single bond or a double bond and X is a single bond when R4 and R5 are hydrogen; Y is a single bond or a double bond; n is 1 to 5, m is 0 to 4; and the non-toxic salts. The prostaglandin ethers possess valuable pharmacological properties as modifiers of smooth muscle activity, gastric secretion, blood pressure, lipolysis and the reproductive system. The compounds also induce labor and menses and they can be used for the relief of asthma and nasal congestion. The compounds are also useful as platelet anti-clumping agents and for the inhibition of peptic ulcers. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4994274-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5238961-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4146553-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5011856-A |
| priorityDate | 1971-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.