abstract |
Compounds of the formula ##STR1## wherein Py is a substituted or unsubstituted 2-, 3- or 4-pyridyl, N-oxidized or quaternized pyridyl group; n A is a group of the formula n n -- ALK--0 -- -- O--ALK -- -- ALK--O--Alk -- n n wherein n Alk is straight or branched chain alkylene of 1 to 6 carbon atoms; n R 1 is a carboxylic acid group, a group which is converted in the human body to a carboxylic acid group or acyl; n R 2 , r 3 and R 4 are each hydrogen, a carboxylic acid group, a group which is converted in the human body to a carboxylic acid group, acyl, hydroxy, alkoxy, aralkoxy, aryloxy, an esterified hydroxy group, nitro, halogen or amino; n May be formulated into pharmaceutical compositions useful for the treatment of hyperglycaemia by combining said compounds with a pharmaceutically acceptable non-toxic inert diluent or carrier. |