http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4051143-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfefd71e9f71a29b3396d6f84f50f855 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 |
| filingDate | 1976-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1977-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69295d50aca2c5a7b12c7c05f138f5b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_824e3c02e92ef8932976a7196f29a681 |
| publicationDate | 1977-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4051143-A |
| titleOfInvention | Process for the production of α-[2-(p-chlorophenoxy)-isobutyryl]-β-nicotinoyl glycol ester |
| abstract | The application discloses a novel improved process for the production of alpha -[2-(p-chlorophenoxy)-isobutyl]- beta -nicotinoyl glycol ester, a known compound having a lipid-lowering effect, by the reaction of alpha -[2-chlorophenoxy)-isobutyryl]- beta -ethyl chloride ester with an alkali salt of nicotinic acid, preferably sodium nicotinate, preferably in a high-boiling polar or dipolar aprotic solvent, especially dimethylformamide, most preferably at a temperature of about 120 DEG - 180 DEG C., and most advantageously in refluxing dimethylformamide. An unpredictable increase in yields of the desired product over yields attainable by previously-available processes is thereby obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7671216-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026377-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923467-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7956198-B2 |
| priorityDate | 1974-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.