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publicationNumber US-4038147-A
titleOfInvention Method for detecting endotoxins
abstract A rapid and reliable method is disclosed for determining the presence or absence of endotoxins in solution, including biological liquids such as transudates and exudates. The method comprises a procedure based upon the alteration of a modified coagulation test system by endotoxins produced by gram-negative microorganisms. The method is particularly useful as reliable aid in the early diagnosis and treatment of infections caused by gram-negative microorganisms and to alert the diagnostician to the possibility of septic shock in an infected host.
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