| abstract |
Allergic hypersensitivity of a number of patients to a large number of allergens is determined by coating a sheet of cellulosic material on both sides with an adherent hydrophobic material so as to leave a plurality of uncoated islands on one side of the sheet which are in register with a plurality of uncoated islands on the other side of the sheet and with the islands so placed that they lie in horizontal and vertical rows on the sheet, contacting each vertical row of islands with a separate identified allergen, contacting each horizontal row of islands with the serum of a patient, contacting all of the islands with an anti-IgE specific antiserum labeled with either a fluorescent material or a radioactive material and then identifying the islands containing fluorescent or radioactive material. Apparatus for carrying out the determination is described. |