http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4008228-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02 |
| filingDate | 1975-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1977-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f31f72572a296b361b9f45f8addf12f5 |
| publicationDate | 1977-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4008228-A |
| titleOfInvention | Process for preparing 3-methyl-3-cephem antibiotics |
| abstract | 7-Acylamino-3-methyl-3-cephem-4-carboxylic acids and esters are prepared via the reductive cleavage of a 3-thio substituted 2-cephem-4-carboxylic acid or ester with hydrogen and Raney nickel or zinc in formic acid and DMF to provide reduction product mixtures of the corresponding 7-substituted 3-methyl-2-cephem-4-acid or ester (I) and 3-exomethylenecepham-4-acid or ester (II). Reduction product mixtures are separable via chromatography and individual I and II are isomerized to 3-methyl-3-cephem antibiotics. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5660711-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5571910-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5847116-A |
| priorityDate | 1971-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 662.