abstract |
Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula <IMAGE> wherein R1 is hydrogen, lower alkanoyl, benzoyl or halobenzoyl, R2 is hydrogen, chlorine or bromine, R3 is carboxyl or lower carbalkoxy, and R4 and R5 are each hydrogen, alkyl of 1 to 5 carbon atoms, mono- or di-hydroxy-(alkyl of 1 to 5 carbon atoms), alkenyl or 2 to 4 carbon atoms, cycloalkyl of 5 to 7 carbon atoms, mono- or di-hydroxy-(cycloalkyl of 5 to 7 carbon atoms) or benzyl, OR A NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALT THEREOF; AND A METHOD OF USING THE SAME AS ANTI-ULCEROGENICS, SECRETOLYTICS, ANTITUSSIVES, AND STIMULANTS OF THE PRODUCTION OF THE SURFACTANT OR ANTIATELECTASIS FACTOR OF THE ALVEOLI. |