abstract |
A compound of the formula: ##SPC1## n Or a pharmaceutically acceptable nontoxic salt thereof wherein n R 1 is hydrogen, straight or branched chain alkyl of 1 to 5 carbon atoms, monoaralkyl of up to 8 carbon atoms, monoaryl, substituted monoaryl, or thienyl; n A is a moiety of the formula: ##EQU1## wherein R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are the same or different and each is hydrogen, straight or branched chain alkyl of 1 to 5 carbon atoms, monoaralkyl of up to 8 carbon atoms, monoaryl, substituted monoaryl, or thienyl; n B is a moiety of the formula: ##SPC2## n Wherein n R 8 , r 9 and R 10 are the same or different and each is hydrogen, fluorine, chlorine, bromine, iodine, lower alkyl, lower alkoxy, lower alkythio, lower alkylsulphonyl, sulphamyl, nitro, cyano, di(lower alkyl)amino, lower alkanoylamino, lower alkanoyloxy, lower alkylsulphonylamino, trifluoromethyl or hydroxy; n E is oxygen or sulphur; and n C is a carbon atom constituting a center of chirality, are useful for their antibacterial activity. |