abstract |
Chlorinated esters of anhydrobenzylpenicillin are reacted with alumina or silica gel to produce fused oxazoline azetidinones. One product may be named methyl 2-(3-benzyl-7-oxo-4-oxa-2,6-diazabicyclo[3,2,0]hept-2-en-6-yl)-3-methy lbut-2-enoate or 2-benzyl-6-(1'-methoxycarbonyl-2'-methylprop-1'-enyl)-1-oxa-3,6-diaza- 4S,5R-bicyclo[3,2,0]hept-2-en-7-one. |