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filingDate 1975-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3627235cb2217c2a0766f3f62976dc0b
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publicationDate 1976-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-3984543-A
titleOfInvention Therapeutic methods employing cyclic aminophosphonic acids
abstract Therapeutic methods employing cyclic aminophosphonic acids having the formula O PARALLEL R-N----P-OH ¦¦ ¦¦NHR ¦¦ O=CC ANGLE O ANGLE PARALLEL OH (CH2)nP ANGLE OH wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 6 carbon atoms and n is an integer from 1 to 4; as well as their water-soluble salts. The cyclic aminophosphonic acids are excellent sequestering agents especially for alkaline earth metal ions, useful in cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficulty soluble calcium salts in the animal body.
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