Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee9023ad76aa762f345c18023c6ff083 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J19-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J19-00 |
filingDate |
1974-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1976-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58fe7d349c367935a8556f0493db7554 |
publicationDate |
1976-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-3963697-A |
titleOfInvention |
Labelled cardiotonic glycosides for use in radioimmunoassay |
abstract |
Disclosed are radioactive cardiotonic glycosides and a process of making such glycosides, the compounds being useful for radioimmunoassay of body fluids for cardiotonic glycoside content. n The novel synthesis comprises reaction of a hydroxyl group of the sugar with a dicarboxylic acid derivative such as a diacid, diacid anhydride or a diacyl halide and thereafter reacting the free carboxylic group with a compound which will undergo electrophilic substitution reactions. A radioactive isotope, preferably 125 I, is reacted via electrophilic substitution with the compound to form the radioactive cardiotonic glycoside. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4296233-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4254111-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4107299-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10889035-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10086542-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2368452-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4133949-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4001402-A |
priorityDate |
1974-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |