http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3935193-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b18d70d8bf538fb533d0aa5cf87170d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
filingDate | 1970-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1976-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_261deca5a6d59171285cde0b5c86de74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f5f2e4f205aacee08b0ab081701d54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e33a8768b371be5a6f30bbda1432bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5adf2a36eb1157ec0063264978d11b15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e61d6dd08370ea861b6b7c48f5fadd98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e18fa1ebbfb8e931f177fb1ab5beda31 |
publicationDate | 1976-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-3935193-A |
titleOfInvention | Diacyl penicillins and methods for their production |
abstract | Novel diacyl penicillins of the formula O CH2-C ANGLE S ANGLE CH3 N-CH-CHC ANGLE ¦¦¦CH3 R-C ANGLE ¦¦¦ O¦¦¦ O=C--N---CH-COOX (I) wherein R is alkyl, cycloalkyl, aryl, aralkyl, phenoxyalkyl, heterocyclic carboxyl excepting isoxazole carboxyl derivatives, or IN WHICH BENZENE RING A may optionally be substituted and B represents a protective group for the amino group, and X is a protective group for the carboxyl group, are produced by reacting a benzyl penicillin ester of the formula S ANGLE CH3 CH2-CO-NH-CH-CHC ANGLE ¦¦¦CH3 O=C--N---CH-COOX (II) wherein X is as defined above, with a chlorinating agent in the presence of tertiary organic base to obtain an imide chloride group-incorporated compound of the formula S ANGLE CH3 CH2-C=N-CH-CHC ANGLE ¦¦¦¦CH3 ClO=C--N---CH-COOX, (III) and then reacting the compound of the last-named formula with carboxylate of the formula R-COOM (IV) wherein M is a metal atom, and R is as defined above. |
priorityDate | 1970-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 706.