abstract |
Octahydrobenzo(6,7)- (or (5,6)-) cyclohepta(1,2,3-de)pyrido- (or pyrrolo-) (2,1-a)isoquinolines, and decahydrobenzo(6,7)- (or (5,6)-) cyclohepta(1,2,3-de)-azepino(2,1-a)isoquinolines and derivatives thereof, optionally substituted on the pyrrolidine, piperidine or azepine ring. The compounds are useful CNS depressants, anticonvulsant and antiinflammatory agents, and methods for their preparation and use are also disclosed. |