| abstract |
A novel benzodiazepine derivatives represented by the formula, and acid addition salts thereof, wherein R1 represents hydrogen, halogen, nitro, C1 4 alkoxy, cyano or trifluoromethyl; R2 represents a group of the formula, WHEREIN R5 and R6 represent hydrogen, halogen, C1 4 alkyl or trifluoromethyl; R3 represents hydrogen, C1 4 alkyl or aralkyl; R4 represents tetrahydropyranyloxy, tetrahydrofuranyloxy, aryloxy, aralkoxy or alkoxyalkoxy; N REPRESENTS AN INTEGER OF 1 TO 4; AND M REPRESENTS ZERO OR 1, WHICH IS PREPARED BY A. REACTING A 1-UNSUBSTITUTED BENZODIAZEPINE DERIVATIVE OF THE FORMULA, with a reactive ester of a compound of the formula, |