| abstract |
Theophylline compounds of the formula, WHEREIN X is oxycarbonyl, carboxyl or carbonyl and R is a lower alkyl group containing from 1 to 5 carbon atoms which have excellent coronary vasodilating effects are produced by reacting a compound having the formula WHEREIN A is hydroxyl, or a carboxyl containing group or a halogenide, acid anhydride or ester thereof, with a compound having the formula WHEREIN B is hydrogen, hydroxyl, or a carboxyl containing group or a halogenide, acid anhydride or ester thereof, and R is defined as before. |