| abstract |
New 1-hydroxy-2-pyridones of the general formula IN WHICH R1 is alkyl of 1 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, cyclohexylalkyl or phenalkyl both having 1 to 3 carbon atoms in the alkylene chain or Alpha -furyl, all of which may be substituted by halogen and R2 to R4 are hydrogen or lower alkyl or 2 adjacent substituents together form a trimethylene or tetramethylene chain, and in which R1 to R4 together contain at least 2 carbon atoms, are prepared by contacting unsaturated delta -keto esters or mixtures thereof with hydroxylamine and subjecting the products to cyclization. The compounds exhibit antimycotic properties. |