Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-26 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
filingDate |
1973-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1975-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62eab2e1508c7cd85f07919f65edec70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f000ce6d69c0092b82747de2f4a3ca6e |
publicationDate |
1975-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-3883500-A |
titleOfInvention |
Process for the manufacture of insulin, analogs and derivatives thereof |
abstract |
D R A W I N G A method for making insulin and certain derivatives thereof from a compound of the formula (I) D R A W I N G wherein X is hydrogen or an S-protective group and n is an integer from two to four, which comprises cleaving any Sprotective groups present and dehydrogenating -SH groups to form S-S bonds to form a compound of the formula (II) BRIDGE BY TREATING THE LATTER COMPOUND WITH AN ACID. Compounds of the formula II. and then eliminating the |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0280534-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5700904-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0280534-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5631347-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0037255-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5646242-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618049-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8900580-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4351764-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE32015-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4215037-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4451396-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4013628-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4014861-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE37971-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4992417-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4992418-A |
priorityDate |
1972-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |