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filingDate 1973-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1975-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-3879557-A
titleOfInvention Compositions for producing {62 -adrenergic stimulant with 4-hydroxy-3-hydroxymethylphenpyl-2-piperidinylcarbinols
abstract 4-Hydroxy-3-hydroxymethylphenyl-2-piperidinylcarbinols prepared by the condensation of an appropriately substituted ether derivative of a methylbenzaldehyde with 2-pyridyl lithium followed by oxidation of the methyl group, removal of the ether group, and reduction of the carboxy pyridine have Beta adrenergic stimulant activity. Erythro and threo diastereoisomers may be conveniently separated.
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