abstract |
This invention relates to prostaglandin D compounds of the general formula: WHEREIN X is -CH2CH2- or cis-CH CH-; wherein one or two of R1, R2 and R3 are methyl and the remainders are hydrogen, or all of R1, R2 and R3 are hydrogen, and indicates attachment of hydroxyl to C-15 in alpha and/or beta configuration. These compounds are useful as hypotensive agents and smooth muscle stimulants. |