| abstract |
N-trityl-imidazoles and salts thereof of the formula WHEREIN R, R1 and R2 are hydrogen, lower alkyl or phenyl, or R1 and R2 together form an anellated benzene ring, X, X'' and X'''' are alkyl of 1 to 12 carbon atoms or an electronegative moiety, and N, N'' AND N'''' ARE AN INTEGER FROM 0 TO 2, OR PHARMACEUTICALLY ACCEPTABLE ACID SALTS THEREOF MAY BE PRODUCED BY REACTING A SILVER SALT OR ALKALI METAL SALT OF AN IMIDAZOLE OF THE FORMULA: WITH A TRITYL HALIDE OF THE FORMULA: WHEREIN THE SUBSTITUENTS ARE AS ABOVE DEFINED AND Hal is halogen. These compounds are useful as antimycotics. |